Robert Langdon awakens in a hospital room in Florence, Italy, with no memory as to what has transpired over the last few days. He suddenly finds himself, again, the target of a major manhunt. But with the help of Dr. Sienna Brooks, and his knowledge of symbology, Langdon will try to regain his freedom, and lost memories, all whilst solving the most intricate riddle he's ever faced.
Four actors in this film all played characters in Marvel Comic Movies - Ben Foster (X-Men: The Last Stand), Spacker Dave (The Punisher), Omar Sy (X-Men: Days of Future Past) and Irrfan Khan (Amazing Spider-Man)
Omar Sy and Irrfan Khan were also in Jurassic World together with Bryce Dallas Howard, the daughter of director Ron Howard
During location filming, its production codename was "Headache", which may be a reference to a concussion suffered by Robert Langdon early in the story
'Inferno' is the fourth book of the Robert Langdon's saga, but it is the third one to be adapted for a film
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