Dhanush 5-aam Vaguppu has an intense script, capturing the feelings of people from different walks of life. The story revolves around the squabbles and misunderstandings between parents in the presence of their children, which affects the child psychologically. One such child is Dhanush, played by Tarun, a Standard V student. He runs away from school to avoid going back home where his parents are always at loggerheads.
A petty thief played by Akhil, robs the child’s school bag. He gets caught soon and Dhanush identifies him in a police line-up. But somehow he manages to escape and in the process takes Dhanush along as well, to a nearby forest where they hide. Ironically, they both enjoy the freedom in their own way until the villain, played by Nizhalgal Ravi comes along.